PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging

Anashia Kayani; Raheel Khan; Najwa Zahoor; Sara Khan; Asma Afzal; Gul Sanam; Aleena Ayesha

doi:10.24911/PJNMed.175-1655996967

2022, Vol: 12, Issue: 1

12 / 1Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

Title page (Sample)

« Previous Article

Original Article

Pak J Nucl Med. 2022; 12(1): 26-30

doi: 10.24911/PJNMed.175-1655996967

PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging

Anashia Kayani, Raheel Khan, Najwa Zahoor, Sara Khan, Asma Afzal, Gul Sanam, Aleena Ayesha.

Abstract
Objectives: To determine the diagnostic accuracy of 18F-labeled fluoro-2-deoxyglucose (18FDG) positron emission tomography/ computed tomography (18FDG-PET/CT) scan for identifying bone marrow involvement in diagnosed patients with lymphoma keeping bone marrow biopsy (BMB) as gold standard.
Study Design: cross-sectional study.
Setting: Department of Radiology, Armed Forces Institute of Radiological Imaging (AFIRI), Rawalpindi from April 26, 2021 to October 25, 2021.
Materials & Methods: A total of 128 cases of lymphoma of age 20-85 years and both genders were included. Patients who had taken treatment for lymphoma or were using bone marrow-stimulant factors or drugs before undergoing PET/CT scanning were excluded. PET/CT imaging was done at AFIRI 6 HD True point PET/CT 1 hour after intravenous injection of 0.2 mCi/kg 18FDG. PET acquisition was performed for 4 minutes per bed position for seven to eight bed positions. Bone marrow was classified into three types based on signal intensity and localization by FDG uptake on PT/CT as diffuse involvement, focal involvement, and normal bone marrow. Findings from 18FDG PET/CT were compared with BMB results for determining the diagnostic accuracy of abdominal FDG PET-CT.
Results: Overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of 18FDG-PET/CT scan for identifying bone marrow involvement in diagnosed patients with lymphoma keeping BMB as gold standard was 95.45%, 93.55%, 94.03%, 95.08%, and 94.53%, respectively.
Conclusion: This study concluded that the diagnostic accuracy of 18FDG-PET/CT scan for identifying bone marrow involvement in diagnosed patients with lymphoma is very high.

Key words: Keywords: lymphoma, positron emission tomography/computed tomography, sensitivity

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Anashia Kayani Articles by Raheel Khan Articles by Najwa Zahoor Articles by Sara Khan Articles by Asma Afzal Articles by Gul Sanam Articles by Aleena Ayesha
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Kayani A, Khan R, Zahoor N, Khan S, Afzal A, Sanam G, Ayesha A. PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pak J Nucl Med. 2022; 12(1): 26-30. doi:10.24911/PJNMed.175-1655996967

Web Style

Kayani A, Khan R, Zahoor N, Khan S, Afzal A, Sanam G, Ayesha A. PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. https://www.pjnmed.com/?mno=67219 [Access: September 05, 2023]. doi:10.24911/PJNMed.175-1655996967

AMA (American Medical Association) Style

Kayani A, Khan R, Zahoor N, Khan S, Afzal A, Sanam G, Ayesha A. PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pak J Nucl Med. 2022; 12(1): 26-30. doi:10.24911/PJNMed.175-1655996967

Vancouver/ICMJE Style

Kayani A, Khan R, Zahoor N, Khan S, Afzal A, Sanam G, Ayesha A. PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pak J Nucl Med. (2022), [cited September 05, 2023]; 12(1): 26-30. doi:10.24911/PJNMed.175-1655996967

Harvard Style

Kayani, A., Khan, . R., Zahoor, . N., Khan, . S., Afzal, . A., Sanam, . G. & Ayesha, . A. (2022) PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pak J Nucl Med, 12 (1), 26-30. doi:10.24911/PJNMed.175-1655996967

Turabian Style

Kayani, Anashia, Raheel Khan, Najwa Zahoor, Sara Khan, Asma Afzal, Gul Sanam, and Aleena Ayesha. 2022. PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pakistan Journal of Nuclear Medicine, 12 (1), 26-30. doi:10.24911/PJNMed.175-1655996967

Chicago Style

Kayani, Anashia, Raheel Khan, Najwa Zahoor, Sara Khan, Asma Afzal, Gul Sanam, and Aleena Ayesha. "PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging." Pakistan Journal of Nuclear Medicine 12 (2022), 26-30. doi:10.24911/PJNMed.175-1655996967

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Kayani, A., Khan, . R., Zahoor, . N., Khan, . S., Afzal, . A., Sanam, . G. & Ayesha, . A. (2022) PET-CT scan can be a reliable alternative to bone marrow Biopsy? Comparison of PET CT scan and marrow biopsy finding in diagnosed cases of lymphoma for staging. Pakistan Journal of Nuclear Medicine, 12 (1), 26-30. doi:10.24911/PJNMed.175-1655996967

Most Viewed Articles

Determination of the optimum filter for 99mTc SPECT breast imaging using a wire mesh collimator
Xianling Dong, M I Saripan, R Mahmud, S Mashohor, Aihui Wang
Pak J Nucl Med. 2017; 7(1): 9-15
» Abstract » doi: 10.24911/PJNMed.7.2

Behaviour of wedges for different field sizes and depths
Sajjad Ahmed Memon, Naeem Ahmed Laghari, Fayaz Hussain Mangi
Pak J Nucl Med. 2017; 7(1): 20-27
» Abstract » doi: 10.24911/PJNMed.7.4

Pre-operative cardiac risk stratification for noncardiac surgery in cancer patients using myocardial perfusion scintigraphy
Iqbal Munir, Amrah Javaid, Khalid Nawaz, Mohammed Hathaf Al-Rowaily, Muaadh Abdualrehman Al-Asbahi
Pak J Nucl Med. 2017; 7(1): 28-33
» Abstract » doi: 10.24911/PJNMed.7.5

Clinical characteristics and long-term outcome of patients with differentiated carcinoma of thyroid with bone metastases: a retrospective study
Sadaf Tufail Butt, Shazia Fatima, Noreen Marwat, Kahkashan Mir, Ayesha Ammar, Mohammad Faheem
Pak J Nucl Med. 2017; 7(1): 34-37
» Abstract » doi: 10.24911/PJNMed.7.6

A brief review of targetted radionuclide therapies
Mohammed Hathaf Al-Rowaily, Daniele Dondi, MarcoChinol, Iqbal Munir, Muaadh Abdualrehman Alasbahi
Pak J Nucl Med. 2017; 7(1): 4-8
» Abstract » doi: 10.24911/PJNMed.7.1

Most Downloaded

Behaviour of wedges for different field sizes and depths
Sajjad Ahmed Memon, Naeem Ahmed Laghari, Fayaz Hussain Mangi
Pak J Nucl Med. 2017; 7(1): 20-27
» Abstract » doi: 10.24911/PJNMed.7.4

Characterization of SIEMENS Symbia T SPECT camera in Monte Carlo simulation environment
Xianling Dong, Mahmud Iqbal Saripan, Rozi Mahmud, Syamsiah Mashohor, Aihui Wang,
Pak J Nucl Med. 2018; 8(1): 18-26
» Abstract » doi: 10.24911/PJNMed.175-1540569779

A historic review of the discovery of the medical uses of radioiodine
Barbara Hertz, Pushan Bharadwaj, Bennett Greenspan
Pak J Nucl Med. 2020; 10(1): 60-63
» Abstract » doi: 10.24911/PJNMed.175-1582813482

Most Cited Articles



About Pakistan Journal of Nuclear Medicine The Pakistan Journal of Nuclear Medicine (PJNM) is the official journal of the Pakistan Society of Nuclear Medicine and the first nuclear medicine journal ... Read more. For best results, please use Internet Explorer or Google Chrome.	Contact Information Pakistan Journal of Nuclear Medicine (PJNM), Room # D-115, D-Block, Department of Medical Sciences, PIEAS, Islamabad, 45650, Pakistan. Email: pjnm@pieas.edu.pk, Phone: +92 51 9248706, Fax: +92 51 9248600 Journal Email: contact@pjnmed.com Billing and Technical Support: contact@discoverpublish.com

POLICIES & JOURNAL LINKS

About Pakistan Journal of Nuclear Medicine

Contact Information

How to cite this article