E-ISSN 2305-1620 | ISSN 2221-0288
 

Original Article

Online Publishing Date:
19 / 04 / 2022

 


Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan

Muhammad Waqar, Muhammad Shahban, Quratulain Soomro, Touqir Ahmad Afridi.


Abstract
Background: Technetium-99m radioisotope is the backbone of any nuclear medicine institute. It is well known that various 99mTclabeled radiopharmaceuticals may get absorbed into the plastic syringes. The consequences of this adsorption are inadequate or inconsistent absorbed dose which produces the inappropriate diagnostic response in patients. The aim of our study was to investigate the true activity administrated to patients and also compare the results of residual activities of the same dose by using different volumes of syringes.
Methods: A total 946 measurements were analyzed in which patients were injected with either 3 or 5 ml syringes and 99mTc was labeled with different pharmaceuticals, i.e., mercaptoacetyltriglycine-3, methoxy-iso-butyl isonitrile, methylenediphosphonic acid (MDP), and technetium pertechnitate. Residual activity was measured for every patient.
Results: The 3 ml syringes have less average retention rate for any radiopharmaceutical as compared to 5 ml syringes. Residual activity for MDP is lower when compared to other radiopharmaceutical for both volumes of syringes. Maximum residual activity for 5 ml syringes happens to be 3.42% of dispensed activity, while for 3 ml syringes it is 2.74% of dispensed activity. The mean effective activities were within the recommended range of EANM and PNRA guidelines.
Conclusion: For all radiopharmaceuticals and both syringes, average residual activity remained well under 1.5% of the activity drawn into syringes, which is insignificant when compared to previous reported results and may not alter the resultant image quality to a larger extent. In hospital, practices should be encouraged to reduce the residual activity as low as possible.

Key words: Tc99m labelled radiopharmaceutical, Residual activity, Nuclear medicine imaging


 
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Pubmed Style

Waqar M, Shahban M, Soomro Q, Afridi TA. Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pak J Nucl Med. 2022; 12(1): 31-36. doi:10.24911/PJNMed.175-1636355717


Web Style

Waqar M, Shahban M, Soomro Q, Afridi TA. Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. https://www.pjnmed.com/?mno=138713 [Access: February 27, 2024]. doi:10.24911/PJNMed.175-1636355717


AMA (American Medical Association) Style

Waqar M, Shahban M, Soomro Q, Afridi TA. Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pak J Nucl Med. 2022; 12(1): 31-36. doi:10.24911/PJNMed.175-1636355717



Vancouver/ICMJE Style

Waqar M, Shahban M, Soomro Q, Afridi TA. Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pak J Nucl Med. (2022), [cited February 27, 2024]; 12(1): 31-36. doi:10.24911/PJNMed.175-1636355717



Harvard Style

Waqar, M., Shahban, . M., Soomro, . Q. & Afridi, . T. A. (2022) Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pak J Nucl Med, 12 (1), 31-36. doi:10.24911/PJNMed.175-1636355717



Turabian Style

Waqar, Muhammad, Muhammad Shahban, Quratulain Soomro, and Touqir Ahmad Afridi. 2022. Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pakistan Journal of Nuclear Medicine, 12 (1), 31-36. doi:10.24911/PJNMed.175-1636355717



Chicago Style

Waqar, Muhammad, Muhammad Shahban, Quratulain Soomro, and Touqir Ahmad Afridi. "Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan." Pakistan Journal of Nuclear Medicine 12 (2022), 31-36. doi:10.24911/PJNMed.175-1636355717



MLA (The Modern Language Association) Style

Waqar, Muhammad, Muhammad Shahban, Quratulain Soomro, and Touqir Ahmad Afridi. "Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan." Pakistan Journal of Nuclear Medicine 12.1 (2022), 31-36. Print. doi:10.24911/PJNMed.175-1636355717



APA (American Psychological Association) Style

Waqar, M., Shahban, . M., Soomro, . Q. & Afridi, . T. A. (2022) Assessment of residual activities of Technetium-99m radiopharmaceuticals to plastic syringes in nuclear medicine scans: 1-year experience at NORIN Nawabshah, Pakistan. Pakistan Journal of Nuclear Medicine, 12 (1), 31-36. doi:10.24911/PJNMed.175-1636355717





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