E-ISSN 2305-1620 | ISSN 2221-0288
 

Case Report

Online Publishing Date:
24 / 03 / 2023

 


Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid.


Abstract
Background: Bone scintigraphy with 99mTc-labelled diphosphonates can identify prostate cancer (PCa) bone metastases with high sensitivity but relatively low specificity. Single photon emission computed tomography /computed tomography (SPECT/CT) can add value to the planar bone scintigraphy in the detection of bone metastases.
Case presentation: We present a diagnosed case of Prostatic Adenocarcinoma of a 62 year old male patient who underwent 99mTc-Methyldiphosphonate (MDP) planar bone scintigraphy followed by SPECT/CT as a part of staging algorithm. Planar bone imaging showed homogeneous and symmetrical tracer uptake throughout the visualized skeleton. As the patient had complaints of urinary obstruction and severe backache: so, the sacrum could not be adequately assessed on planar bone imaging; therefore SPECT/CT of lumbar spine and pelvic region was performed. His regional SPECT-CT study of the lumbar and pelvic region, revealed widespread diffuse tracer avid osteoblastic lesions throughout the visualized lower lumbar spine, sacrum, pelvis and proximal femori, suggestive of skeletal metastases.
Conclusion: We conclude that SPECT/CT scintigraphy has a diagnostic edge over planar bone imaging in detecting bone metastases in prostate cancer patients.

Key words: SPECT/CT, Planar bone scan, Prostate cancer, Prostate specific antigen, equivocal lesions, case report.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Azra Parveen
Articles by Arzoo Fatima Saleem
Articles by Ahmad Qureshy
Articles by Abubaker Shahid
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Parveen A, Saleem AF, Qureshy A, Shahid A. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pak J Nucl Med. 2023; 13(1): 31-36. doi:10.24911/PJNMed.175-1658810334


Web Style

Parveen A, Saleem AF, Qureshy A, Shahid A. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. https://www.pjnmed.com/?mno=89161 [Access: February 27, 2024]. doi:10.24911/PJNMed.175-1658810334


AMA (American Medical Association) Style

Parveen A, Saleem AF, Qureshy A, Shahid A. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pak J Nucl Med. 2023; 13(1): 31-36. doi:10.24911/PJNMed.175-1658810334



Vancouver/ICMJE Style

Parveen A, Saleem AF, Qureshy A, Shahid A. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pak J Nucl Med. (2023), [cited February 27, 2024]; 13(1): 31-36. doi:10.24911/PJNMed.175-1658810334



Harvard Style

Parveen, A., Saleem, . A. F., Qureshy, . A. & Shahid, . A. (2023) Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pak J Nucl Med, 13 (1), 31-36. doi:10.24911/PJNMed.175-1658810334



Turabian Style

Parveen, Azra, Arzoo Fatima Saleem, Ahmad Qureshy, and Abubaker Shahid. 2023. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pakistan Journal of Nuclear Medicine, 13 (1), 31-36. doi:10.24911/PJNMed.175-1658810334



Chicago Style

Parveen, Azra, Arzoo Fatima Saleem, Ahmad Qureshy, and Abubaker Shahid. "Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients." Pakistan Journal of Nuclear Medicine 13 (2023), 31-36. doi:10.24911/PJNMed.175-1658810334



MLA (The Modern Language Association) Style

Parveen, Azra, Arzoo Fatima Saleem, Ahmad Qureshy, and Abubaker Shahid. "Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients." Pakistan Journal of Nuclear Medicine 13.1 (2023), 31-36. Print. doi:10.24911/PJNMed.175-1658810334



APA (American Psychological Association) Style

Parveen, A., Saleem, . A. F., Qureshy, . A. & Shahid, . A. (2023) Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. Pakistan Journal of Nuclear Medicine, 13 (1), 31-36. doi:10.24911/PJNMed.175-1658810334





Most Viewed Articles
Most Accessed Articles

  • Determination of the optimum filter for 99mTc SPECT breast imaging using a wire mesh collimator
    Xianling Dong, M I Saripan, R Mahmud, S Mashohor, Aihui Wang
    Pak J Nucl Med. 2017; 7(1): 9-15
    » Abstract » doi: 10.24911/PJNMed.7.2

  • Behaviour of wedges for different field sizes and depths
    Sajjad Ahmed Memon, Naeem Ahmed Laghari, Fayaz Hussain Mangi
    Pak J Nucl Med. 2017; 7(1): 20-27
    » Abstract » doi: 10.24911/PJNMed.7.4

  • Pre-operative cardiac risk stratification for noncardiac surgery in cancer patients using myocardial perfusion scintigraphy
    Iqbal Munir, Amrah Javaid, Khalid Nawaz, Mohammed Hathaf Al-Rowaily, Muaadh Abdualrehman Al-Asbahi
    Pak J Nucl Med. 2017; 7(1): 28-33
    » Abstract » doi: 10.24911/PJNMed.7.5

  • Clinical characteristics and long-term outcome of patients with differentiated carcinoma of thyroid with bone metastases: a retrospective study
    Sadaf Tufail Butt, Shazia Fatima, Noreen Marwat, Kahkashan Mir, Ayesha Ammar, Mohammad Faheem
    Pak J Nucl Med. 2017; 7(1): 34-37
    » Abstract » doi: 10.24911/PJNMed.7.6

  • A brief review of targetted radionuclide therapies
    Mohammed Hathaf Al-Rowaily, Daniele Dondi, MarcoChinol, Iqbal Munir, Muaadh Abdualrehman Alasbahi
    Pak J Nucl Med. 2017; 7(1): 4-8
    » Abstract » doi: 10.24911/PJNMed.7.1

  • Most Downloaded
    Top Downloaded Articles

  • Behaviour of wedges for different field sizes and depths
    Sajjad Ahmed Memon, Naeem Ahmed Laghari, Fayaz Hussain Mangi
    Pak J Nucl Med. 2017; 7(1): 20-27
    » Abstract » doi: 10.24911/PJNMed.7.4

  • Determination of the optimum filter for 99mTc SPECT breast imaging using a wire mesh collimator
    Xianling Dong, M I Saripan, R Mahmud, S Mashohor, Aihui Wang
    Pak J Nucl Med. 2017; 7(1): 9-15
    » Abstract » doi: 10.24911/PJNMed.7.2

  • Characterization of SIEMENS Symbia T SPECT camera in Monte Carlo simulation environment
    Xianling Dong, Mahmud Iqbal Saripan, Rozi Mahmud, Syamsiah Mashohor, Aihui Wang,
    Pak J Nucl Med. 2018; 8(1): 18-26
    » Abstract » doi: 10.24911/PJNMed.175-1540569779

  • A historic review of the discovery of the medical uses of radioiodine
    Barbara Hertz, Pushan Bharadwaj, Bennett Greenspan
    Pak J Nucl Med. 2020; 10(1): 60-63
    » Abstract » doi: 10.24911/PJNMed.175-1582813482

  • A brief review of targetted radionuclide therapies
    Mohammed Hathaf Al-Rowaily, Daniele Dondi, MarcoChinol, Iqbal Munir, Muaadh Abdualrehman Alasbahi
    Pak J Nucl Med. 2017; 7(1): 4-8
    » Abstract » doi: 10.24911/PJNMed.7.1

  • Most Cited Articles
    Most Cited Articles