E-ISSN 2305-1620 | ISSN 2221-0288
 

Review Article

Online Publishing Date:
21 / 06 / 2021

 


Sentinel lymph node biopsy in oncologic care: a review

Giorgio Caturegli, Ashwani Rajput.


Abstract
Sentinel lymph nodes (SLNs) have for centuries been recognized as reliable and effective filters of foreign material, including tumor cells. Since the mid-20th century, this principle has been applied to oncologic care through sentinel lymph node biopsy (SLNB), which detects and quantifies the extent of regional metastasis. First pioneered in parotid tumors, the technique has since expanded to many branches of oncology including breast, melanoma, head and neck, gastrointestinal, and gynecologic tumors. Across these varied pathologies, SLNB has repeatedly demonstrated non-inferiority to traditionally more extensive lymphatic dissections, which are associated with higher rates of infectious, lymphatic, and neuropathic complications. In an era of ever increasing management options, this technique also provides prognostic and predictive information key to therapeutic selection. This paper reviews the history of the practice of SLNB and its evolution over the decades in a number of oncologic disciplines.

Key words: Sentinel lymph node biopsy, scintigraphy, breast cancer, melanoma, oncology.


 
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Pubmed Style

Caturegli G, Rajput A. Sentinel lymph node biopsy in oncologic care: a review. Pak J Nucl Med. 2021; 11(1): 43-49. doi:10.24911/PJNMed.175-1615983181


Web Style

Caturegli G, Rajput A. Sentinel lymph node biopsy in oncologic care: a review. https://www.pjnmed.com/?mno=65066 [Access: February 27, 2024]. doi:10.24911/PJNMed.175-1615983181


AMA (American Medical Association) Style

Caturegli G, Rajput A. Sentinel lymph node biopsy in oncologic care: a review. Pak J Nucl Med. 2021; 11(1): 43-49. doi:10.24911/PJNMed.175-1615983181



Vancouver/ICMJE Style

Caturegli G, Rajput A. Sentinel lymph node biopsy in oncologic care: a review. Pak J Nucl Med. (2021), [cited February 27, 2024]; 11(1): 43-49. doi:10.24911/PJNMed.175-1615983181



Harvard Style

Caturegli, G. & Rajput, . A. (2021) Sentinel lymph node biopsy in oncologic care: a review. Pak J Nucl Med, 11 (1), 43-49. doi:10.24911/PJNMed.175-1615983181



Turabian Style

Caturegli, Giorgio, and Ashwani Rajput. 2021. Sentinel lymph node biopsy in oncologic care: a review. Pakistan Journal of Nuclear Medicine, 11 (1), 43-49. doi:10.24911/PJNMed.175-1615983181



Chicago Style

Caturegli, Giorgio, and Ashwani Rajput. "Sentinel lymph node biopsy in oncologic care: a review." Pakistan Journal of Nuclear Medicine 11 (2021), 43-49. doi:10.24911/PJNMed.175-1615983181



MLA (The Modern Language Association) Style

Caturegli, Giorgio, and Ashwani Rajput. "Sentinel lymph node biopsy in oncologic care: a review." Pakistan Journal of Nuclear Medicine 11.1 (2021), 43-49. Print. doi:10.24911/PJNMed.175-1615983181



APA (American Psychological Association) Style

Caturegli, G. & Rajput, . A. (2021) Sentinel lymph node biopsy in oncologic care: a review. Pakistan Journal of Nuclear Medicine, 11 (1), 43-49. doi:10.24911/PJNMed.175-1615983181





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