E-ISSN 2305-1620 | ISSN 2221-0288
 

Original Research (Original Article) 


Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi.

Abstract
Background: Currently, intermittent pneumatic compression (IPC) is a standard method of lymphedema treatment. Recently, the effect of this modality in patients with limb arterial insufficiency has been researched. It has been suggested that the arterial inflow to the long bones is also increased by IPC. The purpose of this paper is to assess the effect of lower limb IPC on the blood flow as well as delayed bone uptake. Methods: In this prospective study, we evaluated 30 patients who were referred for whole body bone scan to our Nuclear Medicine Department. All the patients had been examined by a vascular surgeon for ruling out any peripheral neuropathy, vasculopathy or ulcer in the lower limbs. Also, all the patients were questioned about hypertension, diabetes mellitus, and other chronic diseases with peripheral complications. Following 925MBq of 99mTc-methylenediphosphonate (MDP) injection, perfusion and blood pool images of both legs as well as static delayed images were done after the completion of IPC. Results: Thirty patients (10 male) with the age range of 3084 years (mean = 53.4) were included. Radiotracer uptake in flow and blood pool images in the compressed limb was significantly more than the contralateral limb, however, on delayed images, no significant difference was noted between two limbs. Conclusion: Although IPC can significantly increase blood flow of the compressed limb, MDP uptake on the delayed images was not increased. According to this study, IPC may not be useful as a technique to increase releasing chemotherapy drugs or other substances to the bone and promoting bone growth.

Key words: Intermittent pneumatic compression, IPC, bone scan, MDP uptake, vascular flow.


 
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Pubmed Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pak J Nucl Med. 2018; 8(1): 3-7. doi:10.24911/PJNMed.175-1529737505


Web Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. http://www.pjnmed.com/?mno=302526 [Access: January 21, 2020]. doi:10.24911/PJNMed.175-1529737505


AMA (American Medical Association) Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pak J Nucl Med. 2018; 8(1): 3-7. doi:10.24911/PJNMed.175-1529737505



Vancouver/ICMJE Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pak J Nucl Med. (2018), [cited January 21, 2020]; 8(1): 3-7. doi:10.24911/PJNMed.175-1529737505



Harvard Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi (2018) Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pak J Nucl Med, 8 (1), 3-7. doi:10.24911/PJNMed.175-1529737505



Turabian Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. 2018. Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pakistan Journal of Nuclear Medicine, 8 (1), 3-7. doi:10.24911/PJNMed.175-1529737505



Chicago Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. "Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?." Pakistan Journal of Nuclear Medicine 8 (2018), 3-7. doi:10.24911/PJNMed.175-1529737505



MLA (The Modern Language Association) Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi. "Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?." Pakistan Journal of Nuclear Medicine 8.1 (2018), 3-7. Print. doi:10.24911/PJNMed.175-1529737505



APA (American Psychological Association) Style

Susan Shafiei, Narjess Ayati, Hamideh Sadra, Gholam Hosein Kazemzadeh, Samira Zare namdar, Baharak Attar, Seyed Rasoul Zakavi (2018) Is intermittent pneumatic compression (IPC) an appropriate method for increasing 99m Tc-MDP uptake in bone scan?. Pakistan Journal of Nuclear Medicine, 8 (1), 3-7. doi:10.24911/PJNMed.175-1529737505





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