E-ISSN 2305-1620 | ISSN 2221-0288
 

Original Research (Original Article) 


Bone SPECT-CT in the diagnosis and staging of osseous metastases

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva.

Abstract
Aims: The combined application of baseline whole-body bone scan (WBBS), followed by more specific techniques such as SPECT-CT fusion is an advanced approach for the diagnosis, differential diagnosis and staging of osseous metastases. The purpose of this work was to assess SPECT-CT images in diagnosis of suspected bone metastases in patients with oncological diseases. <br><br> Methods: This study included 89 patients (54 females, 35 males aged 18-92 yrs) with different types of tumours. All patients underwent routine WBBS with 99mTc-MDP as well as target SPECT-CT imaging using a double-headed SPECT-CT camera coupled with a 2-slice CT scanner. <br><br> Results: The skeletal findings with previously uncertain character were classified as definitely benign, indeterminate or definitely malignant. These included: 1) 33% benign degenerative lesions, 2) 28% single osseous metastases, 3) 10% direct bone infiltration, 4) 15% cold or osteolytic bone lesions, 5) 12% mixed type lesions and 6) 2% single extraosseous lesions. <br><br> Conclusion: The most important clinical application of bone SPECT-CT imaging is for differential diagnosis between degenerative and metastatic foci with abnormal tracer uptake and similar scintigraphic appearance on the WBBS.


 
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Pubmed Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pak J Nucl Med. 2015; 5(1): 37-44.


Web Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. Bone SPECT-CT in the diagnosis and staging of osseous metastases. http://www.pjnmed.com/?mno=284633 [Access: December 14, 2018].


AMA (American Medical Association) Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pak J Nucl Med. 2015; 5(1): 37-44.



Vancouver/ICMJE Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pak J Nucl Med. (2015), [cited December 14, 2018]; 5(1): 37-44.



Harvard Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva (2015) Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pak J Nucl Med, 5 (1), 37-44.



Turabian Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. 2015. Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pakistan Journal of Nuclear Medicine, 5 (1), 37-44.



Chicago Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. "Bone SPECT-CT in the diagnosis and staging of osseous metastases." Pakistan Journal of Nuclear Medicine 5 (2015), 37-44.



MLA (The Modern Language Association) Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva. "Bone SPECT-CT in the diagnosis and staging of osseous metastases." Pakistan Journal of Nuclear Medicine 5.1 (2015), 37-44. Print.



APA (American Psychological Association) Style

Sonya Sergieva, Elena Alexandrova, Bojil Robev, Iglika Mihaylova, Milena Dimcheva (2015) Bone SPECT-CT in the diagnosis and staging of osseous metastases. Pakistan Journal of Nuclear Medicine, 5 (1), 37-44.





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